Microphthalmia transcription factor regulates the expression of the novel osteoclast factor GPNMB
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چکیده
منابع مشابه
Microphthalmia transcription factor regulates the expression of the novel osteoclast factor GPNMB.
Microphthalmia transcription factor (MITF) regulates bone homeostasis by inducing expression of critical genes associated with osteoclast function. Gpnmb is a macrophage-enriched gene that has also been shown to be expressed in osteoblasts. Here, we have shown gpnmb to be highly induced in maturing murine osteoclasts. Microarray expression profile analysis identified gpnmb as a potential target...
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ژورنال
عنوان ژورنال: Gene
سال: 2008
ISSN: 0378-1119
DOI: 10.1016/j.gene.2008.01.014